Thanks, to a developer named –viperboy- you can easily root your Asus Transformer Prime in one click. The root method works on all versions of the Prime even the latest OTA and it is by far the easiest root method available.
- Download ViperMod PrimeTime v4.1 (Windows download, Linux download)
- Plug in your device install the drivers locate in the .zip you downloaded above
- Run the viperMOD PrimeTime.exe in the .zip file
- Enjoy your rooted Prime
Head over to the official thread to thank –viperboy- and show your support, also you can ask any question you have over there.